[The consensus of Chinese experts on refined analysis of immune cell subsets in peripheral blood by multi-parameter

    Insights

    Refined analysis of peripheral blood immune cell subsets is crucial for clinical diagnosis and health management. This expert consensus standardizes multiparameter flow cytometry methods for precise immune cell detection and application.

    Area of Science:

    • Immunology
    • Clinical Diagnostics
    • Laboratory Medicine

    Context:

    • Accurate detection of immune cell subsets is vital for diagnosing diseases, managing health, and advancing research.
    • Existing methods require refinement for in-depth study of functional subsets, immune aging, and non-lymphocyte immune cells.
    • Multiparameter flow cytometry is a key technology for immune cell subset analysis and immune function evaluation.

    Purpose:

    • To standardize refined detection methods and protocols for peripheral blood immune cell subsets using flow cytometry.
    • To promote the application of precise immune cell subset analysis in clinical practice.
    • To establish reference intervals for clonality and immune aging, enabling individualized monitoring and treatment.

    Summary:

    • This expert consensus provides standardized protocols for multiparameter flow cytometry to analyze peripheral blood immune cell subsets.
    • It addresses the need for refined analysis to support clinical diagnosis, disease management, and research into immune cell functions.
    • The consensus aims to enhance the clinical utility of flow cytometry for immune cell subset detection.

    Impact:

    • Improved accuracy and consistency in immune cell subset detection.
    • Enhanced clinical decision-making for various diseases and health management strategies.
    • Facilitation of further research into the clinical significance of diverse immune cell populations.