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[The consensus of Chinese experts on refined analysis of immune cell subsets in peripheral blood by multi-parameter
Insights
Refined analysis of peripheral blood immune cell subsets is crucial for clinical diagnosis and health management. This expert consensus standardizes multiparameter flow cytometry methods for precise immune cell detection and application.
Area of Science:
- Immunology
- Clinical Diagnostics
- Laboratory Medicine
Context:
- Accurate detection of immune cell subsets is vital for diagnosing diseases, managing health, and advancing research.
- Existing methods require refinement for in-depth study of functional subsets, immune aging, and non-lymphocyte immune cells.
- Multiparameter flow cytometry is a key technology for immune cell subset analysis and immune function evaluation.
Purpose:
- To standardize refined detection methods and protocols for peripheral blood immune cell subsets using flow cytometry.
- To promote the application of precise immune cell subset analysis in clinical practice.
- To establish reference intervals for clonality and immune aging, enabling individualized monitoring and treatment.
Summary:
- This expert consensus provides standardized protocols for multiparameter flow cytometry to analyze peripheral blood immune cell subsets.
- It addresses the need for refined analysis to support clinical diagnosis, disease management, and research into immune cell functions.
- The consensus aims to enhance the clinical utility of flow cytometry for immune cell subset detection.
Impact:
- Improved accuracy and consistency in immune cell subset detection.
- Enhanced clinical decision-making for various diseases and health management strategies.
- Facilitation of further research into the clinical significance of diverse immune cell populations.
Abstract:
The detection of immune cell subsets plays a very important role in the clinical diagnosis and treatment of various benign and malignant diseases and health management. In order to better carry out in-depth research on different functional immune cell subsets, establish reference intervals for clonality related indicators, establish special reference intervals for immune aging, individualized dynamic monitoring and treatment recovery, and discover the clinical significance of immune cells other than lymphocytes, it is urgent to analyze the peripheral blood immune cell subsets in a refined way. Multiparameter flow cytometry is an important technical method to detect immune cell subsets and evaluate immune function. In order to standardize the refined detection methods and protocols of peripheral blood immune cell subsets by flow cytometry, and further promote its application in clinical diagnosis and treatment of diseases and health management, Laboratory Medicine Committee of Chinese Association of Integrative Medicine (LMC-CAIM) organized experts to formulate this expert consensus.
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