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An unusual case of B-cell lymphoma of the scalp
Nadeem Chaudhry1, Abid Qureshi2, Sindhuri Gollamudi3
1Department of Plastic Surgery, The Brooklyn Hospital Center, 121 Dekalb Ave, Brooklyn, NY 11201, United States.
Insights
Primary cutaneous follicular cell lymphoma (PCFCL) is a rare skin lymphoma. This case report highlights PCFCL originating in the scalp, emphasizing the need for established management protocols.
Area of Science:
- Oncology
- Dermatology
- Hematology
Background:
- B-cell lymphoma is a type of non-Hodgkin lymphoma originating from B lymphocytes.
- Primary cutaneous B-cell lymphoma (PCBCL) is a subtype that develops in the skin without extracutaneous involvement.
- Scalp tumors are predominantly benign, with malignant neoplasms being rare.
Observation:
- Primary cutaneous follicular cell lymphoma (PCFCL) is the most common type of cutaneous lymphoma.
- PCFCL typically presents with an indolent course and a favorable prognosis.
- Reports of PCFCL originating in the scalp are exceptionally rare.
Findings:
- This report details a rare case of PCFCL arising in the scalp.
- The case underscores the infrequent occurrence of this specific lymphoma subtype in this location.
- Established management strategies for PCFCL include surgical removal, radiotherapy, topical, and intralesional therapies.
Implications:
- Increased awareness of PCFCL in the scalp is crucial for timely diagnosis and treatment.
- This case highlights the importance of considering rare differentials for scalp lesions.
- Further research and established management guidelines are needed for PCFCL of the scalp.
Abstract:
B-cell lymphoma is a lymphoproliferative non-Hodgkin lymphoma arising from B cells, a type of immune lymphocytes that produces antibodies in the follicles of lymph nodes. Primary cutaneous B-cell lymphoma (PCBCL), a subtype of B cell lymphoma, originates within cutaneous tissue without evidence of extracutaneous involvement. There are very few reports of PCBCLs originating in the scalp. The most common tumors of the scalp are usually benign with only 1%-2% being malignant, most being basal cell carcinoma, squamous cell carcinoma, or melanoma. Primary cutaneous follicular cell lymphoma (PCFCL) is regarded as the most common lymphoma of the skin with an indolent course and favorable prognosis due to the response rate to treatment methods such as surgical removal with local radiotherapy, topical drugs, and intralesional therapies. This report highlights a rare case of PCFCL originating in the scalp, to raise awareness of a topic that requires continued established management.
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