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Immunoglobulin G4-related Dacryoadenitis Successfully Treated with Baricitinib

Atsuhiko Suenaga1,2, Naoki Sawa1,3, Yuki Oba1

  • 1Department of Nephrology and Rheumatology, Toranomon Hospital Kajigaya, Japan.

Internal Medicine (Tokyo, Japan)
|January 31, 2024
PubMed

Insights

Immunoglobulin G4-related dacryoadenitis, a rare condition causing lacrimal gland enlargement, was effectively treated with baricitinib when steroids failed. This treatment also improved associated atopic dermatitis.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition.
  • IgG4-related dacryoadenitis, an ocular manifestation of IgG4-RD, presents with lacrimal gland enlargement.
  • Steroid therapy is the first-line treatment, but resistance can occur.

Keywords:
IgG4 related diseaseIgG4-related dacryoadenitisatopic dermatitisbaricitinib

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