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Published on: October 1, 2015
Global Bibliometric and Visualized Analysis of Research on Lactoferrin from 1978 to 2024
Hong Gu1, Yiming Wang1, Yating Wang1
1Department of Nutrition and Food Hygiene, School of Public Health, Jilin University, Changchun, 130021, China.
Insights
Lactoferrin (LF) research shows significant growth, with emerging trends in LF nanoparticles and gut microbiota interactions. This bibliometric analysis highlights LF
Area of Science:
- Biochemistry
- Immunology
- Materials Science
Background:
- Lactoferrin (LF) is an iron-bound protein (approx. 80 kDa) with diverse biological activities, including antibacterial, antiviral, immunomodulatory, and anticancer properties.
- Understanding the research landscape and trends of lactoferrin is crucial for advancing scientific discovery in its various applications.
Purpose of the Study:
- To conduct a bibliometric analysis of lactoferrin (LF) research to identify key trends, influential contributors, and emerging research frontiers.
- To explore the global research output and collaboration patterns in the field of lactoferrin.
Main Methods:
- Bibliometric analysis of publications from the Web of Science Core Collection database.
- Utilized CiteSpace and VOSviewer software for analyzing countries, institutions, authors, journals, and keywords.
- Included 9382 publications related to lactoferrin from 1987 onwards.
Main Results:
- Research on lactoferrin has shown a consistent year-on-year increase since 1987, with contributions from 124 countries and 725 institutions.
- Valenti Piera is identified as the most prolific author, with 1256 authors analyzed.
- Key emerging research areas with high burst strength include nanoparticles, gut microbiota, antioxidant activity, and in vitro digestion.
Conclusions:
- Lactoferrin (LF) possesses significant research value across multiple scientific disciplines.
- The study identifies LF nanoparticles and LF's impact on gut microbiota as rapidly developing and promising research avenues.
- Bibliometric analysis provides valuable insights for future research directions in lactoferrin.
Scope:
Lactoferrin (LF) is an iron-bound protein with a molecular weight of about 80 kDa. LF has many biological functions such as antibacterial, antiviral, immunomodulatory, and anticancer. The purpose of this study is to explore the research trend of LF through bibliometric analysis.
Methods And Results:
The search is conducted in the Web of Science Core Collection database, and then the publications information of LF related literature is exported. Based on CiteSpace and VOSviewer software, countries, institutions, authors, journals, keywords, and so on are analyzed. Since 1987, a total of 9382 literature have been included, and the number of papers related to LF has increased year by year. These publications come mainly from 124 countries and 725 institutions. Of the 1256 authors analyzed, Valenti Piera is the one with the most publications. The burst strength of gut microbiota, antioxidant, nanoparticles, and in vitro digestion are 21.3, 15.63, 23.03, and 13.51, respectively. They represent the frontier of research in this field and are developing rapidly.
Conclusion:
This study shows that LF has important research value. The study of LF nanoparticles and the effects of LF on the gut microbiota are an emerging field that helps to explore new research directions.
