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Published on: September 14, 2019
Cryptosporidium-Induced Myocarditis: A Unique Case Study
Fatima Eltayeb1, Emily Rawlinson1, Raymol Keelan1
1Acute Medicine, Wythenshawe Hospital, Manchester, GBR.
Insights
This case study details a rare instance of myocarditis (inflammation of the heart muscle) caused by Cryptosporidium infection in an otherwise healthy individual. It highlights the importance of considering unusual infectious agents and the utility of cardiac MRI in diagnosing myocarditis.
Area of Science:
- Infectious Diseases
- Cardiology
- Parasitology
Background:
- Myocarditis, inflammation of the heart muscle, is typically caused by viral infections.
- Non-viral causes, especially in immunocompetent individuals, are less common but significant.
- Cryptosporidium is a protozoan parasite usually associated with gastrointestinal infections.
Abstract:
Myocarditis is the inflammation of the myocardium. While viral infections commonly cause it, we present a unique case of Cryptosporidium-induced myocarditis in an immunocompetent individual. A 33-year-old man presenting with acute chest pain and loose stools was found to have troponin levels of over 1,000 ng/L. Initial viral screen tests were negative, and an inpatient echocardiogram showed an insignificant rim of pericardial effusion. Computed tomography of the coronary arteries showed no evidence of coronary artery disease. He was later discharged with outpatient cardiac magnetic resonance imaging (MRI), which subsequently showed acute focal sub-epicardial fibronecrosis, consistent with acute myocarditis. Following this, stool cultures were found to be positive for Cryptosporidium hominis, a protozoan parasite. After a further review of the history, it was discovered that the patient had recently been exposed to dead pigeons and faeces at a workplace construction site. This rare presentation demonstrates the importance of considering less common infectious agents even in immunocompetent patients, as there is only one other case study ever published. Furthermore, it highlights the increasing value of using cardiac MRI as a non-invasive investigation for myocarditis.
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