Related Experiment Video
Updated: Jan 27, 2026

Horizontal Gel Electrophoresis for Enhanced Detection of Protein-RNA Complexes
Published on: July 28, 2017
Meeting Review on India EMBO lecture course on RNA-protein complexes: from molecular assembly to physiological
Debleena Mukhopadhyay1, Nasrin Banu Mohammad Faisal1, Chloe Leray2
1National Centre for Cell Science, University of Pune Campus, Pune University Road, Ganeshkhind, Pune, Maharashtra 411007, India.
Insights
This lecture course explored RNA-protein interactions, focusing on their role in cellular functions, disease, and molecular assembly. Key discussions covered recent advances in understanding these complexes and their impact on biological processes.
Area of Science:
- Molecular Biology
- Cell Biology
- Biochemistry
Background:
- RNA-protein interactions are crucial for cellular functions.
- Dysregulation of these interactions contributes to various diseases.
- Understanding the assembly and function of RNA-protein complexes is vital.
Purpose of the Study:
- To review recent advances in RNA-protein interactions.
- To discuss the role of RNA-protein complexes in cellular functions and disease.
- To highlight new methodologies in studying these complexes.
Main Methods:
- The content is based on presentations and discussions from the India EMBO lecture course.
- Includes insights from flash talks, poster presentations, and methodological workshops.
- Focuses on research covering fundamental architecture and higher-order cellular functions.
Main Results:
- Recent advances in RNA-protein interactions and their regulatory roles were presented.
- The impact of dysregulated post-transcriptional processes in disease was highlighted.
- New insights into complex assembly, cellular functions, and plasticity were shared.
Conclusions:
- RNA-protein complexes play a critical role in cellular functions and disease.
- Further research into their assembly and regulation is essential.
- Methodological advancements are enhancing our understanding of these vital molecular machines.
Abstract:
The India EMBO lecture course 'RNA-protein complexes: from molecular assembly to physiological functions and disease' was held at The National Centre for Cell Science, Pune, India, from February 24 to 28, 2025. The major theme of the lecture series centred on the recent advances in RNA-protein interactions and their role in regulating complex assembly or condensation as well as cellular functions and plasticity. Additionally, the course highlighted the impact of dysregulated post-transcriptional processes in various diseases. Speakers from various biological disciplines presented their research on both the fundamental architecture of RNA and protein complexes and their contributions to higher-order cellular functions. The course also featured flash talks and poster presentations selected from abstract submissions, alongside special methodological workshops on omics and phase separation. This Meeting Review reflects on the event's key discussions, drawing attention to the overarching themes and main conclusions.
Related Concept Videos
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Protein Complex Assembly
Protein Complexes with Interchangeable Parts
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
Protein Complexes with Interchangeable Parts
RNA Polymerase II Accessory Proteins
Assembly of Signaling Complexes
Interaction domains in cell signaling
Interaction domains recognize exposed features of their binding partners containing post-translationally modified sequences,...

