Psammoma Bodies in Cervical Liquid-Based Cytology of a Kyleena User

José Eleutério Junior1,2, Vitor Alencar Arrais de Souza1, Renata Mírian Nunes Eleutério2

  • 1Department of Women, Children and Adolescent Health, Faculty of Medicine, Federal University of Ceará, Fortaleza, Brazil.

Insights

Psammoma bodies are rare calcified structures found in Pap smears of intrauterine device (IUD) users. This study observed these laminated calcified structures in liquid-based cervical cytology, confirming their presence in IUD users.

Area of Science:

  • Gynecologic pathology
  • Cytopathology
  • Cervical cancer screening

Background:

  • Psammoma bodies are rare findings in Pap smears, particularly among intrauterine device (IUD) users.
  • Previous reports indicate a prevalence ranging from 0.0047% to 0.009%.

Purpose of the Study:

  • To report the observation of psammoma bodies in liquid-based cytology samples from the uterine cervix in IUD users.
  • To describe the cytomorphological features of these structures.

Main Methods:

  • Analysis of liquid-based cytology samples from the uterine cervix.
  • Identification of laminated calcified structures consistent with psammoma bodies.
  • Correlation with patient history of IUD use.

Main Results:

  • Observed laminated calcified structures resembling psammoma bodies.
  • These structures were found amidst squamous, glandular, and inflammatory cells.
  • The findings are consistent with psammoma bodies in the context of IUD use.

Conclusions:

  • Psammoma bodies can be identified in liquid-based cervical cytology in IUD users.
  • These findings, though rare, are important for accurate cytologic interpretation.
  • Further research may explore the significance and potential causes of psammoma bodies in this population.