Related Experiment Video
Updated: Aug 8, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Continuous extrapleural intercostal nerve block with continuous infusion of lidocaine after thoracotomy. A
E Sullivan1, F W Grannis, B Ferrell
1Department of Thoracic Oncology, City of Hope National Medical Center, Duarte Calif., USA.
Insights
Continuous extrapleural intercostal block with lidocaine offers promising pain relief after thoracotomy. This technique demonstrated good pain control with minimal toxicity, warranting further investigation.
Area of Science:
- Anesthesiology
- Pain Management
- Thoracic Surgery
Background:
- Continuous extrapleural intercostal block (EPIB) using bupivacaine is an established analgesic method post-thoracotomy.
- Limited data exists on the efficacy and safety of lidocaine for continuous EPIB.
Purpose of the Study:
- To retrospectively evaluate the analgesic efficacy and safety of continuous EPIB with lidocaine in patients undergoing posterolateral thoracotomy.
Main Methods:
- A retrospective review of 18 consecutive posterolateral thoracotomies over 6 months.
- Continuous infusion of 1% lidocaine hydrochloride (1 mg/kg/h) via a posterior parietal pleural catheter for 3 days post-surgery.
- Patients also received patient-controlled analgesia with morphine sulfate.
Main Results:
- Average verbal analog pain scores ranged from 2.8 to 3.14 over 3 days.
- Mean daily morphine sulfate consumption was below 40 mg.
- One patient had a transient serum lidocaine level slightly above the toxic threshold without clinical signs of toxicity.
- No major respiratory complications or deaths were reported.
Conclusions:
- Continuous EPIB with lidocaine appears to be a safe and potentially effective adjuvant for managing postthoracotomy pain.
- Further confirmation through prospective randomized studies is recommended to establish its efficacy definitively.
Abstract:
Continuous extrapleural intercostal block (EPIB) with bupivacaine has been reported to be an effective analgesic technique in patients after thoracotomy. We report a retrospective study of EPIB using a continuous infusion of 1% lidocaine hydrochloride at a dose of 1 mg/kg/h. A posterior parietal pleural pocket was created and cannulated with a 16-g polyethylene catheter. Lidocaine was perfused over a 3-day period following surgery. Patients also had access to morphine sulfate via patient-controlled analgesia. Eighteen consecutive posterolateral thoracotomies (in 17 patients) performed during a 6-month period were reviewed. Serum lidocaine exceeded the toxic level of 5 microgram/mL in only one patient, a 104.5-kg man who had a level of 5.9 micrograms/mL on postoperative day 2 but experienced no clinical toxicity. Pain was evaluated by verbal analog scores (0 = no pain and 10 = worst pain), which averaged 3.02, 3.14, and 2.8 in the 3 days following surgery. Mean total daily MS doses were 24.3, 37.75, and 34.32 mg (range, 0 to 94 mg). Sedation was scored on a 1 to 5 scale. Mean scores were 2.78, 2.56, and 2.6. No patient died or had a major respiratory complication. Continuous EPIB with lidocaine appears to be a promising adjuvant technique in the management of postthoracotomy pain. Effectiveness needs to be confirmed in a prospective randomized study.
Related Concept Videos
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...
Endoscopic Studies II: Thoracocentesis
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...

