Related Experiment Video

Updated: Aug 14, 2026

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques
11:06

Laparoscopic Technique for Serial Collection of Liver and Mesenteric Lymph Nodes in Macaques

Published on: May 2, 2017

[CT-morphologic aspects of the liver in patients with HIV infection]

H Schedel1, L Wicht, G Rögler

  • 1Strahlenklinik und Poliklinik, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.

Aktuelle Radiologie
|July 1, 1994
PubMed

Insights

CT scans reveal frequent liver abnormalities in HIV-infected patients. Rare causes like cryptococcosis and steatosis require careful consideration in diagnosing focal liver lesions in immunocompromised individuals.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Hepatology

Background:

  • Computed tomography (CT) is crucial for staging HIV patients.
  • Immunocompromised individuals exhibit atypical disease presentations.
  • Liver pathologies are common in HIV-infected populations.

Observation:

  • CT scans of the liver in HIV-infected patients demonstrate frequent pathological findings.
  • Interpretation requires considering an extended spectrum of differential diagnoses and atypical manifestations.
  • This study examines CT findings in 76 HIV-infected patients undergoing abdominal staging.

Findings:

  • Common findings include hepatomegaly, splenomegaly, lymphoma, and bowel inflammation.
  • Rare but significant causes of focal hepatic lesions include Cryptococcus neoformans infection, hepatitis, and localized steatosis.
  • Atypical presentations necessitate a broad differential diagnosis.

Implications:

  • Radiologists must be aware of rare hepatic manifestations in HIV patients.
  • Enhanced vigilance for unusual findings can improve diagnostic accuracy.
  • This knowledge aids in timely and appropriate patient management.

More Related Videos

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis10:12

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis

Published on: September 11, 2019

Mapping Hepatic Stellate Cell Morphology in Mouse Models of Liver Fibrosis06:55

Mapping Hepatic Stellate Cell Morphology in Mouse Models of Liver Fibrosis

Published on: February 13, 2026

Related Concept Videos

Liver Histology01:27

Liver Histology

The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Cirrhosis II: Pathophysiology01:24

Cirrhosis II: Pathophysiology

Cirrhosis is a progressive chronic liver injury caused by prolonged inflammation, excessive fibrotic remodeling, and impaired regeneration. Over time, repeated hepatic insults disrupt the liver’s architecture and function, leading to reduced blood flow, impaired bile drainage, and diminished metabolic capacity.Pathophysiology of cirrhosisCirrhosis arises from three main responses to chronic liver damage: inflammation, immune activation, and hepatocyte death. These processes lead to structural...