Related Experiment Video
Updated: Aug 10, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
[Hodgkin's disease with a giant thymic cyst]
K Takeshita1, T Terashima, T Urano
1Department of Medicine, School of Medicine, Keio University, Tokyo, Japan.
Insights
A large thymic cyst with Hodgkin
Area of Science:
- Oncology
- Pathology
Background:
- Mediastinal masses can present diagnostic challenges.
- Anterior mediastinal masses require thorough investigation.
Observation:
- An asymptomatic 26-year-old male presented with an abnormal mediastinal shadow.
- Chest CT revealed a large anterior mediastinal mass with para-aortic lymphadenopathy.
- The mass exhibited multiloculated low-density areas with enhancing parenchymal rims.
Findings:
- Surgical resection of the cystic tumor and lymph nodes was performed.
- Pathological examination confirmed a thymic cyst.
- The cyst wall contained Hodgkin's lymphoma, including lacunar and Reed-Sternberg cells.
Implications:
- This case highlights a rare presentation of Hodgkin's lymphoma within a thymic cyst.
- Accurate pathological diagnosis is crucial for effective treatment planning.
- Further research into rare mediastinal malignancies is warranted.
Abstract:
An asymptomatic 26-year-old male was admitted to our hospital for examination of an abnormal mediastinal shadow on chest X-ray. Chest CT showed a large mass in the anterior mediastinum with marked para-aortic lymph node enlargement. The mass consisted mostly of multiloculated low-density areas surrounded by a rim of enhancing parenchymal tissue. Both the cystic tumor and surrounding lymph nodes were resected. The tumor measured 18 x 10 x 2 cm and contained about 450 ml of straw colored fluid. Pathological examination revealed a thymic cyst, the wall of which was composed of Hodgkin's lymphoma cells and nodular sclerotic lesions containing many lacunar cells and Reed-Sternberg cells.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Hyperthyroidism I: Introduction
Graves Disease II: Pathophysiology
Goiter
