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Massage therapy is associated with enhancement of the immune system's cytotoxic capacity
G Ironson1, T Field, F Scafidi
1Touch Research Institute, University of Miami School of Medicine, Fl, USA.
Insights
Daily massage therapy significantly boosted immune function in gay men, increasing Natural Killer (NK) cells and cytotoxicity. Massage also reduced anxiety and cortisol levels without impacting HIV progression markers.
Area of Science:
- Immunology
- Psychoneuroimmunology
- Integrative Medicine
Background:
- Massage therapy is increasingly explored for its health benefits.
- The impact of massage on immune function, particularly in vulnerable populations like HIV+ individuals, requires further investigation.
- Understanding the interplay between psychological state, neuroendocrine function, and immune response is crucial.
Purpose of the Study:
- To investigate the effects of daily massage on immune markers, neuroendocrine function, and psychological well-being in gay men, including those with HIV.
- To assess whether massage influences HIV disease progression markers.
- To explore correlations between psychological changes and immune responses.
Main Methods:
- A study involving 29 gay men (20 HIV+, 9 HIV-) who received daily massages for one month.
- A within-subject control for 11 HIV+ participants (one month with massage, one month without).
- Measurement of immune cells (NK cells, CD8 cells), HIV progression markers (CD4, CD4/CD8 ratio), neuroendocrine markers (cortisol, catecholamines), and psychological states (anxiety, relaxation).
Main Results:
- Significant increases in Natural Killer (NK) cell number and cytotoxicity.
- Significant increases in cytotoxic CD8 cells and soluble CD8.
- Significant decrease in cortisol levels and trends toward decreased catecholamines; no changes in HIV disease progression markers.
- Significant decreases in anxiety and increases in relaxation, correlated with NK cell increases.
Conclusions:
- Daily massage therapy enhances cytotoxic immune capacity in gay men.
- Massage may offer benefits beyond psychological well-being, impacting immune function.
- Findings suggest potential therapeutic implications for massage in managing immune status for individuals with chronic illnesses, including HIV and cancer.
Abstract:
Twenty-nine gay men (20 HIV+, 9 HIV-) received daily massages for one month. A subset of 11 of the HIV+ subjects served as a within subject control group (one month with and without massages). Major immune findings for the effects of the month of massage included a significant increase in Natural Killer Cell number, Natural Killer Cell Cytotoxicity, soluble CD8, and the cytotoxic subset of CD8 cells. There were no changes in HIV disease progression markers (CD4, CD4/CD8 ratio, Beta-2 microglobulin, neopterin). Major neuroendocrine findings, measured via 24 hour urines included a significant decrease in cortisol, and nonsignificant trends toward decrease of catecholamines. There were also significant decreases in anxiety and increases in relaxation which were significantly correlated with increases in NK cell number. Thus, there appears to be an increase in cytotoxic capacity associated with massage. Implications for HIV+ men as those with other illnesses, particularly cancer, are discussed.
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