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[Low affinity Fc receptor for IgE (Fc epsilon R II/CD23)]

Y Gon1, J Yodoi

  • 1Department of Biological Responses, Kyoto University.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|February 1, 1996
PubMed

Insights

The Fc epsilon RII/CD23 is a low-affinity receptor for IgE, playing diverse biological roles. This review summarizes recent advancements in understanding this crucial molecule.

Area of Science:

  • Immunology
  • Molecular Biology

Context:

  • The Fc epsilon RII/CD23 (CD23) is a low-affinity receptor central to immunoglobulin E (IgE) regulation.
  • CD23 mediates various biological functions, impacting immune responses and cellular interactions.

Purpose:

  • To provide a comprehensive review of the latest research on Fc epsilon RII/CD23.
  • To consolidate current knowledge on the structure, function, and biological significance of CD23.

Summary:

  • Fc epsilon RII/CD23 is a low-affinity receptor that binds to IgE.
  • This molecule is involved in a wide array of biological processes.
  • Recent findings regarding CD23's multifaceted roles are discussed.

Impact:

  • Enhances understanding of IgE-mediated immunity.
  • Provides a foundation for future research into CD23-targeted therapies.
  • Highlights the significance of CD23 in various physiological and pathological conditions.

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