Cervical lymphadenopathy in the eastern province of Saudi Arabia
1Department of Pathology, College of Medicine, King South University, Riyadh, Kingdom of Saudi Arabia.
Insights
Cervical lymph node biopsies revealed malignancy in 42% of cases, non-specific reactive changes in 30%, and granulomatous conditions in 28%. This study analyzes histological findings from Saudi Arabia.
Area of Science:
- Pathology
- Oncology
- Histopathology
Background:
- Cervical lymphadenopathy is a common clinical presentation.
- Accurate diagnosis of cervical lymph node lesions is crucial for patient management.
- Previous studies on cervical lymph node biopsy findings in Saudi Arabia are limited.
Purpose of the Study:
- To analyze the histopathological spectrum of cervical lymph node biopsies.
- To determine the prevalence of malignant, reactive, and granulomatous conditions in cervical lymph nodes.
- To compare findings with international literature.
Main Methods:
- Retrospective analysis of 1,250 cervical lymph node biopsies.
- Histopathological examination of tissue samples.
- Data collection over a 12-year period (1982-1983).
Main Results:
- Malignant conditions (primary or metastatic) were observed in 42% of biopsies.
- Non-specific reactive changes were present in 30% of cases.
- Granulomatous conditions accounted for 28% of the biopsies.
Conclusions:
- Malignancy is the most frequent finding in cervical lymph node biopsies in this Saudi Arabian cohort.
- A significant proportion of cases present with reactive or granulomatous changes.
- Findings highlight the importance of thorough histopathological evaluation for accurate diagnosis.
Abstract:
A total of 1,250 cervical lymph node biopsies were performed at King Fahad University Hospital, Al Khobar, kingdom of Saudi Arabia during a 12-year period (1982-1983). This restrospective study revealed that in 42% of the biopsies, there were histological features of either primary or metastatic malignant conditions, while 30% exhibited non-specific reactive changes. Granulomatous conditions accounted for 28% of the cases. The data is compared with similar published studies with a review and discussion of relevant literature.
