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Published on: March 8, 2018
Adenocarcinoma of the iris pigment epithelium
C W Spraul1, D d'Heurle, H E Grossniklaus
1Department of Ophthalmology, Emory University School of Medicine, Atlanta, Ga, USA.
Insights
A rare low-grade adenocarcinoma of the iris pigment epithelium was diagnosed in an 81-year-old man. Local resection is recommended for growing iris pigment epithelium lesions.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Pigmented lesions of the iris require careful diagnosis.
- Adenomatous proliferations of the iris pigment epithelium are exceptionally rare.
Observation:
- An 81-year-old male presented with a pigmented lesion on the right iris.
- The lesion was surgically removed for examination.
Findings:
- Microscopic examination, including immunohistochemistry and electron microscopy, confirmed a diagnosis of low-grade adenocarcinoma.
- The tumor originated from the iris pigment epithelium.
Implications:
- This case highlights an extremely rare form of iris tumor.
- Local resection is the recommended treatment for growing lesions of the iris pigment epithelium.
- Further research is needed as metastasis has not been observed.
Abstract:
We treated an 81-year-old man with a pigmented lesion of his right iris. The lesion was locally excised. Light microscopic examination, including immunohistochemistry, and electron microscopic examination were performed. The diagnosis was low-grade adenocarcinoma arising from the iris pigment epithelium. Adenomatous proliferations of the iris pigment epithelium are exceedingly rare and have not been shown to metastasize. Local resection is recommended if the lesion exhibits growth.
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