Adenocarcinoma of the iris pigment epithelium

C W Spraul1, D d'Heurle, H E Grossniklaus

  • 1Department of Ophthalmology, Emory University School of Medicine, Atlanta, Ga, USA.

Insights

A rare low-grade adenocarcinoma of the iris pigment epithelium was diagnosed in an 81-year-old man. Local resection is recommended for growing iris pigment epithelium lesions.

Area of Science:

  • Ophthalmology
  • Oncology
  • Pathology

Background:

  • Pigmented lesions of the iris require careful diagnosis.
  • Adenomatous proliferations of the iris pigment epithelium are exceptionally rare.

Observation:

  • An 81-year-old male presented with a pigmented lesion on the right iris.
  • The lesion was surgically removed for examination.

Findings:

  • Microscopic examination, including immunohistochemistry and electron microscopy, confirmed a diagnosis of low-grade adenocarcinoma.
  • The tumor originated from the iris pigment epithelium.

Implications:

  • This case highlights an extremely rare form of iris tumor.
  • Local resection is the recommended treatment for growing lesions of the iris pigment epithelium.
  • Further research is needed as metastasis has not been observed.