Related Experiment Video
Updated: Aug 8, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
[Interstitial cystitis]
T Hanus1, L Zámecník, M Janský
1Urologická klinika 1. LF UK a VFN, Praha.
Insights
Interstitial cystitis (IC), a painful bladder condition primarily affecting women, presents with varying forms diagnosed via cystoscopy. Histopathology reveals distinct subtypes, guiding diverse treatment approaches.
Area of Science:
- Urology
- Pathology
Abstract:
Interstitial cystitis (IC) is a complex of painful mictional symptomatology of unknown etiology. Is occurs more frequently in women. By cystoscopy the ulcerative and non-ulcerative form is differentiated. A typical diagnosis symptom are glomerulations during cystoscopy under general anaesthesia. There are diagnostic criteria which rule out IC. Histopathologically the following are differentiated: classical IC with proliferation of mastocytes in the detrusor, detrusor myopathy and eosinophil cystitis. Treatment includes intervesical instillation of various substances, transurethral procedures or supratrifonal cystectomy, incl. enterocystoplasty.
Related Concept Videos
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Urinary Tract Infection I: Introduction
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Imaging Studies VI: Voiding Cystourethrography and Cystography
Urologic Endoscopic Procedure: Cystoscopic Examination

