Splenic lymphocytes with circulating villous lymphocytes--a case report

D Gupta1, S Rani, T Singh

  • 1Department of Pathology and Medicine, Maulana Azad Medical College, New Delhi, India.

Indian Journal of Cancer
|December 1, 1996
PubMed

Insights

A rare case of splenic lymphoma with circulating villous lymphocytes (SLVL) was diagnosed in a young male. This presentation highlights unusual clinical features of SLVL, emphasizing diagnostic rarity.

Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Splenic lymphoma with circulating villous lymphocytes (SLVL) is a rare hematologic malignancy.
  • Diagnosis typically relies on peripheral blood and bone marrow examination.

Observation:

  • A 25-year-old male presented with hepatomegaly, splenomegaly, and fever.
  • Clinical presentation was unusual for the typical demographic of SLVL.

Findings:

  • Morphology, cytochemistry, and immunocytochemistry confirmed SLVL.
  • Circulating villous lymphocytes were identified in peripheral blood and bone marrow.

Implications:

  • This case underscores the importance of considering rare diagnoses in young patients with atypical presentations.
  • Highlights the diagnostic utility of integrated hematologic analyses for SLVL.
  • Contributes to understanding the spectrum of SLVL presentation.