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Published on: March 5, 2016
Splenic lymphocytes with circulating villous lymphocytes--a case report
1Department of Pathology and Medicine, Maulana Azad Medical College, New Delhi, India.
Insights
A rare case of splenic lymphoma with circulating villous lymphocytes (SLVL) was diagnosed in a young male. This presentation highlights unusual clinical features of SLVL, emphasizing diagnostic rarity.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Splenic lymphoma with circulating villous lymphocytes (SLVL) is a rare hematologic malignancy.
- Diagnosis typically relies on peripheral blood and bone marrow examination.
Observation:
- A 25-year-old male presented with hepatomegaly, splenomegaly, and fever.
- Clinical presentation was unusual for the typical demographic of SLVL.
Findings:
- Morphology, cytochemistry, and immunocytochemistry confirmed SLVL.
- Circulating villous lymphocytes were identified in peripheral blood and bone marrow.
Implications:
- This case underscores the importance of considering rare diagnoses in young patients with atypical presentations.
- Highlights the diagnostic utility of integrated hematologic analyses for SLVL.
- Contributes to understanding the spectrum of SLVL presentation.
Abstract:
A 25 years old male presented with hepatomegaly splenomegaly and fever. He was diagnosed as splenic lymphoma with circulating villous lymphocytes (SLVL) on morphology, cytochemistry and immunocytochemistry performed on peripheral blood and bone marrow smears. Case is being presented because of rarity and unusual presentation at young age.

