细胞巨乳病毒视网膜炎与内肠道德克萨米他松植入物注射相关

Marissa K Shoji1, Jesse D Sengillo1, Akaanksh Shetty1

  • 1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Insights

细胞巨病毒 (CMV) 视网膜炎是德克萨米他植入物注射后的一种罕见并发症,即使在免疫能力强的患者中也是如此. 及时识别和治疗对于预防严重视力丧失至关重要.

科学领域:

  • 眼科医生 眼科 眼科
  • 传染性疾病 传染性疾病
  • 视网膜外科手术 视网膜外科手术

背景情况:

  • 内皮质类固醇注射,如甲植入物,通常用于各种眼部炎症状况.
  • 虽然局部免疫抑制通常是安全的,但可能会导致机会性感染.
  • 细胞巨病毒 (CMV) 视网膜炎是已知的视力丧失的原因,特别是在免疫功能低下的个体中.

研究的目的:

  • 在德克萨米他植入物注射后,在免疫能力较强的患者中报告细胞巨乳病毒 (CMV) 视网膜炎病例.
  • 审查有关在类似治疗后发生的CMV视网膜炎的现有文献.

主要方法:

  • 一个75岁的男性患者的病例报告,在注射德甲植入物后视力下降.
  • 眼科检查,水性聚合酶连锁反应 (PCR) 检测CMV,并对免疫缺陷进行实验室评估.
  • 对以前记录的病例进行了全面的文献审查.

主要成果:

  • 患者出现严重的视力丧失和视网膜炎的临床症状;水性PCR证实了CMV感染.
  • 该患者没有潜在的免疫缺陷,突出显示了CMV在免疫能力强的主体中重新激活的潜力.
  • 文献综述发现了8个先前的病例,其中大多数与潜在的免疫失调有关.

结论:

  • 冠状病毒视网膜炎是一种罕见但严重的Dexamethasone植入物注射的并发症.
  • 这种并发症甚至可以发生在免疫能力较强的患者中,强调需要提高临床怀疑度.
  • 早期诊断和及时的抗病毒治疗对于减轻不可逆转的视力损伤风险至关重要.
抽象的

No abstract available in PubMed .

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