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[反复发烧,持续的细胞衰竭]

Y Miao1, J Zhang2, H Zhang3

  • 1Department of Hematology, Lymphoma Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Department of Oncology, Department of Hematology, Affiliated Hospital of Nantong University, Nantong 226001, China.

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
|October 27, 2025
PubMed

Insights

血管内大B细胞淋巴瘤 (IVLBCL) 是一种罕见的癌症. 这一案例突出了IVLBCL的诊断挑战和攻击性,强调了诊断和治疗中需要多学科合作的必要性.

科学领域:

  • 血液学 血液学 血液学
  • 在瘤学瘤学.
  • 罕见疾病 罕见疾病

背景情况:

  • 血管内大B细胞淋巴瘤 (IVLBCL) 是一种不常见的大B细胞淋巴瘤的亚型.
  • 患者经常出现非特异性症状,使早期诊断复杂化.

研究的目的:

  • 报告一个具有挑战性的IVLBCL病例最初被误诊.
  • 强调在诊断和管理IVLBCL时采用多学科方法的重要性.
  • 为临床实践提供有关IVLBCL诊断和治疗的见解.

主要方法:

  • 一个64岁的女性病例报告,有沃尔登斯特罗姆巨型球蛋白血病史.
  • 使用正子发射断层扫描/计算机断层扫描 (PET/CT) 和上腺活检进行诊断.
  • 治疗包括R-CHOP化疗,随后确定中枢神经系统 (CNS) 的参与.
  • 在上腺活检审查后,诊断被修改为IVLBCL.

主要成果:

  • 患者最初出现了复发性发烧和全细胞衰竭.
  • 在PET/CT检测出上腺扩大,导致初步诊断为扩散型大B细胞淋巴瘤,未另有说明.
  • 在初始化疗后发现了中枢神经系统透.
  • 最终的诊断被证实为IVLBCL,但尽管进行了积极的治疗,疾病仍在进展,导致患者死亡.

结论:

  • 由于IVLBCL的罕见性和非特异性呈现,它带来了重大诊断挑战.
  • 涉及成像,病理学和临床专业知识的多学科合作对于准确的IVLBCL诊断至关重要.
  • IVLBCL的攻击性需要迅速和适当的管理策略,尽管结果在许多情况下仍然很差.
抽象的

No abstract available in PubMed .

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