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单个供体血小板在含容器染色的血小板添加剂溶液中的异常色变色:一种罕见的观察

Suvetha Rajendran1, Harsha Unni1, Mohandoss Murugesan1

  • 1Transfusion Medicine, Malabar Cancer Centre, Postgraduate Institute of Oncology Sciences and Research, Thalassery, India.

Journal of clinical apheresis
|December 28, 2025
PubMed

Insights

存储在血小板添加剂溶液 (PAS) 中的异常黄斑外观与捐赠者的高白血症有关. 这一案例突出了潜在的捐赠者衍生色素转移,表明需要重新评估血液成分视觉检查标准.

科学领域:

  • 输血医学 输血医学
  • 血液学 血液学 血液学
  • 血液成分加工 血液成分加工

背景情况:

  • 血小板添加剂溶液 (PAS) 用于延长血小板缩物的储存时间.
  • 视觉检查是评估血液成分质量的主要方法.
  • 血液制品中性变色通常与血液溶解或肝脏功能障碍有关.

研究的目的:

  • 报告一个非同寻常的黄色变的病例在一个非血小板 (AP) 单位.
  • 调查变色的原因及其对血小板质量的影响.
  • 讨论对血液储存实践的影响.

主要方法:

  • 一个AP单位的案例报告,出现了黄色变色和袋子染色.
  • 无菌培养和初始血小板形态评估.
  • 捐赠者评估,包括胆红素水平.
  • 在存储过程中进行血小板功能测试.

主要成果:

  • 该AP单元显示明显的黄斑变色和袋子染色,尽管无菌培养和保存初始形态.
  • 捐赠者评估显示轻度非结合性高 bilirubinemia.
  • 存储5天后,血小板功能降低了.
  • 捐赠者衍生的颜料被认为是变色的来源.

结论:

  • 尽管很少见,但PAS悬浮血小板中的性外观可能表明与捐赠者相关的色素转移.
  • 这一案例表明,目前的视觉检查方法可能无法检测出所有质量问题.
  • 对血液成分的接受标准进行重新评估是有必要的.
抽象的

No abstract available in PubMed .

关键词:
血小板的表.血小板添加剂溶液的解决方案血小板功能 血小板功能黄色变色变色的情况

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