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Descubrimientos accidentales en imágenes de resonancia magnética cerebral de 1000 voluntarios asintomáticos
G L Katzman1, A P Dagher, N J Patronas
1Diagnostic Radiology Department, National Institutes of Health, Bethesda, MD 20892, USA.
JAMA
|July 15, 1999
Resumen
Las exploraciones de resonancia magnética cerebral en individuos sanos revelan anormalidades inesperadas en el 18% de los casos. Una pequeña fracción de estos hallazgos incidentales, incluidos los tumores cerebrales, requieren atención médica urgente.
Área de la Ciencia:
- Neurología Neurología.
- Radiología Radiología.
- Imágenes médicas de imágenes médicas.
Sus antecedentes:
- Estudios previos sobre hallazgos cerebrales incidentales fueron sesgados por preocupaciones clínicas preexistentes.
- La prevalencia de anormalidades inesperadas en una población verdaderamente sana no se ha estudiado.
Objetivo del estudio:
- Para determinar la prevalencia de hallazgos incidentales en las exploraciones de resonancia magnética cerebral en una población sana y asintomática.
- Para evaluar la tasa de anormalidades inesperadas sin sesgo de selección.
Principales métodos:
- Análisis retrospectivo de 1000 imágenes de resonancia magnética cerebral de voluntarios sanos (de 3 a 83 años).
- Se confirmó que los participantes estaban sanos y asintomáticos a través del examen médico y la historia.
- Los hallazgos se clasificaron por urgencia de referencia requerida (ninguna, rutinaria, urgente, inmediata).
Principales resultados:
- El 82% de las exploraciones de resonancia magnética cerebral fueron normales.
- El 18% de las exploraciones revelaron anomalías incidentales.
- Se necesitó una derivación urgente para el 1,1% de los sujetos, identificando al menos el 0,2% con tumores cerebrales primarios.
Conclusiones:
- Las personas asintomáticas pueden presentar varias anomalías cerebrales.
- Los hallazgos incidentales en poblaciones sanas ofrecen datos cruciales sobre la prevalencia de la enfermedad.
- Un pequeño porcentaje de estos hallazgos requieren una evaluación médica inmediata y una investigación adicional.
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