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Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy
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Caracterización molecular del receptor de la hormona que concentra la melanina en el cuerpo

Y Saito1, H P Nothacker, Z Wang

  • 1Department of Pharmacology, University of California, Irvine 92697-4625, USA.

Nature
|July 27, 1999
PubMed
Resumen

Los investigadores identificaron el ligando natural para un receptor huérfano acoplado a la proteína G (GPCR), SLC-1, como la hormona que concentra la melanina (MCH). Este neuropéptido regula el comportamiento de alimentación y activa las vías SLC-1, lo que sugiere un potencial terapéutico para la regulación del consumo de alimentos.

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