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Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
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El entrenamiento de ejercicios aeróbicos puede revertir los cambios circulatorios periféricos relacionados con la
P A Beere1, S D Russell, M C Morey
1Department of Medicine, Divisions of Cardiology and Geriatrics, Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC 27710, USA.
Circulation
|September 8, 1999
Resumen
El ejercicio aeróbico regular mejora el consumo máximo de oxígeno en adultos mayores al mejorar el flujo sanguíneo a los músculos. Este estudio muestra que el entrenamiento invierte los declives relacionados con la edad, mejorando el suministro de oxígeno y la utilización en el ejercicio de los músculos.
Área de la Ciencia:
- Fisiología del ejercicio fisiológico.
- Investigación sobre el envejecimiento de la investigación.
- Respuestas cardiovasculares al ejercicio.
Sus antecedentes:
- El consumo máximo de oxígeno disminuye con la edad, pero el impacto del entrenamiento físico en las respuestas centrales y periféricas en los adultos mayores sigue sin estar claro.
- Comprender estas respuestas es crucial para desarrollar intervenciones efectivas de ejercicio para un envejecimiento saludable.
Objetivo del estudio:
- Investigar las contribuciones cardiovasculares centrales y periféricas a la disminución relacionada con la edad en el consumo máximo de oxígeno.
- Para comparar los efectos del entrenamiento físico en estas respuestas en hombres mayores frente a hombres más jóvenes.
Principales métodos:
- Medición invasiva de las respuestas cardiovasculares centrales y periféricas durante la ergometría de ciclo graduado.
- Comparación de respuestas antes y después de un programa de entrenamiento físico de 3 meses en 10 hombres mayores y 13 más jóvenes.
Principales resultados:
- Ambos grupos aumentaron el consumo máximo de oxígeno con el entrenamiento; el rendimiento cardíaco máximo se mantuvo sin cambios.
- La diferencia de oxígeno arteriovenoso sistémico aumentó con el entrenamiento, lo que explica la mejora del consumo máximo de oxígeno.
- El flujo sanguíneo máximo en las piernas aumentó significativamente en los hombres mayores, mientras que la extracción de oxígeno en las piernas mejoró en los hombres más jóvenes.
Conclusiones:
- La disminución relacionada con la edad en el consumo máximo de oxígeno está relacionada con el descondicionamiento que afecta la distribución de la salida cardíaca a los músculos.
- El entrenamiento físico puede revertir estos efectos, mejorando la función cardiovascular y la utilización de oxígeno en adultos mayores.
- La reducción de la reserva de salida cardíaca contribuye a la disminución de la capacidad de ejercicio asociada a la edad.
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