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Updated: Jul 14, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

Una interacción del dominio PDZ regulada por una quinasa controla la clasificación endocítica del receptor

T T Cao1, H W Deacon, D Reczek

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco 94143, USA.

Nature
|September 28, 1999
PubMed
Resumen

Los dominios PDZ y la actina regulan la clasificación de los receptores beta2-adrenérgicos en los endosomas. La fosforilación por GRK-5 controla esta interacción, afectando el tráfico de receptores y la transducción de señales.

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