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El glaucoma inducido por taxanos
Lancet (London, England)
|October 8, 1999
Resumen
La quimioterapia con Doxetaxel para el cáncer de mama puede causar glaucoma. Esta afección ocular reapareció cuando el paciente fue tratado más tarde con paclitaxel, otro medicamento de quimioterapia.
Área de la Ciencia:
- Oftalmología Oftalmología.
- Oncología médica Oncología médica.
Sus antecedentes:
- El tratamiento del cáncer de mama metastásico a menudo implica quimioterapia.
- El doxetaxel y el paclitaxel son agentes quimioterapéuticos comunes utilizados en el tratamiento del cáncer de mama.
Objetivo del estudio:
- Para informar de un raro caso de glaucoma inducido por quimioterapia.
- Para resaltar la potencial toxicidad ocular de la quimioterapia a base de taxanos.
Principales métodos:
- Informe de caso que detalla el curso clínico de un paciente.
- Revisión de la historia clínica y los registros de tratamiento del paciente.
- Examen y diagnóstico oftalmológico.
Principales resultados:
- Glaucoma desarrollado durante el tratamiento con doxetaxel para el cáncer de mama metastásico.
- Los síntomas de glaucoma se resolvieron después de la interrupción del doxetaxel.
- El glaucoma se repitió en el tratamiento posterior con paclitaxel.
Conclusiones:
- El doxetaxel y el paclitaxel pueden inducir el glaucoma.
- Los oftalmólogos y oncólogos deben ser conscientes de este posible efecto secundario.
- Se recomienda una estrecha vigilancia ocular durante la terapia con taxanos.
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