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Updated: Jul 10, 2026

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PPARdelta es un objetivo regulado por APC de fármacos antiinflamatorios no esteroideos

T C He1, T A Chan, B Vogelstein

  • 1Johns Hopkins Oncology Center, Johns Hopkins University, Baltimore, Maryland 21231, USA.

Cell
|November 11, 1999
PubMed
Resumen

El supresor tumoral APC normalmente reprime el PPARdelta en el cáncer colorrectal (CRC). Los medicamentos antiinflamatorios no esteroideos (AINE) como el sulindac inhiben este gen, lo que podría bloquear el crecimiento del tumor del CCR.

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