Jove
Visualize
Contáctanos

Videos de Conceptos Relacionados

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

3.3K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
3.3K
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

1.3K
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
1.3K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.9K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

826
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
826
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

790
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
790
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

805
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
805

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

The inverse problem for cardiac arrhythmias.

Chaos (Woodbury, N.Y.)·2023
Same author

In-treatment HDL cholesterol levels and development of new diabetes mellitus in hypertensive patients: the LIFE Study.

Diabetic medicine : a journal of the British Diabetic Association·2013
Same author

Impact of overweight and obesity on cardiac benefit of antihypertensive treatment.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2011
Same author

Changes in electrocardiographic left ventricular hypertrophy and risk of major cardiovascular events in isolated systolic hypertension: the LIFE study.

Journal of human hypertension·2010
Same author

Clustered metabolic abnormalities blunt regression of hypertensive left ventricular hypertrophy: the LIFE study.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2009
Same author

Impact of diabetes on treatment-induced changes in left ventricular structure and function in hypertensive patients with left ventricular hypertrophy. The LIFE study.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2009
Same journal

Eugene Braunwald, MD, 1929-2026.

Circulation·2026
Same journal

AHA/ACC/ESC/WHF Expert Consensus Document: Second Universal Definition of Heart Failure (2026).

Circulation·2026
Same journal

Advancing Quality in the Evaluation, Surveillance, and Management of Aortic Stenosis: A Report From the AHA Target: AS Registry.

Circulation·2026
Same journal

Heart Failure Occurring in the Perinatal Period: A Scientific Statement From the American Heart Association.

Circulation·2026
Same journal

Correction to: 2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Circulation·2026
Same journal

Correction to: The Natural History of Massive Left Ventricular Hypertrophy in Pediatric Hypertrophic Cardiomyopathy: A Multiregistry Analysis.

Circulation·2026
Ver todos los artículos relacionados
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Video Experimental Relacionado

Updated: May 5, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K

Geometría y función del ventrículo izquierdo antes del síncope neuralmente mediado.

J E Liu1, R T Hahn, K M Stein

  • 1Department of Medicine, Division of Cardiology, The New York Hospital-Cornell Medical Center, New York, NY 10021, USA.

Circulation
|February 23, 2000
PubMed
Resumen
Este resumen es generado por máquina.

La síncope neuralmente mediada no es causada por el aumento de la contractilidad ventricular izquierda (LV). La reducción de la función y el volumen de LV durante la inclinación vertical están vinculados a respuestas positivas a las pruebas de inclinación de la mesa en pacientes con síncope.

Más Videos Relacionados

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

2.8K
Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
08:45

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients

Published on: April 18, 2025

1.7K

Videos de Experimentos Relacionados

Last Updated: May 5, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.1K
Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

2.8K
Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
08:45

Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients

Published on: April 18, 2025

1.7K

Área de la Ciencia:

  • Cardiología Cardiología.
  • Fisiología Fisiología Fisiología.

Sus antecedentes:

  • El síncope neuralmente mediado está relacionado con un aumento del acortamiento fraccionario (FS) del ventrículo izquierdo (LV) durante las pruebas de inclinación.
  • Esto sugiere que la estimulación del mecanorreceptor LV causa hipotensión refleja, pero el FS se ve afectado por la carga posterior y la carga previa, no solo por la contractilidad.

Objetivo del estudio:

  • Para investigar el papel de la contractilidad de LV en la síncope neuralmente mediada.
  • Para comparar las medidas de rendimiento de LV corregidas para el estrés sistólico final (ESS) en pacientes con respuestas positivas frente a respuestas negativas en la prueba de inclinación de la mesa.

Principales métodos:

  • La ecocardiografía se utilizó para evaluar el rendimiento de LV en 21 pacientes con síncope inexplicable durante las posiciones de supina y inclinación vertical.
  • Las medidas de LV, incluido el volumen del trazo, FS y el acortamiento de la pared media corregido por estrés, se compararon entre los grupos de inclinación positiva y inclinación negativa.

Principales resultados:

  • En la posición supina, ambos grupos mostraron un rendimiento similar de LV.
  • Durante la inclinación vertical, el grupo con inclinación positiva exhibió un menor volumen de golpe, un menor acortamiento de la pared media corregido por el estrés y una disminución del FS endocárdico.
  • El grupo de inclinación positiva también mostró una mayor reducción en ESS y FS temprano durante la inclinación.

Conclusiones:

  • La reducción del estrés sistólico terminal (ESS), el volumen de LV y la función de la cámara durante la inclinación vertical inicial se correlacionan con las respuestas de inclinación positiva en pacientes con síncope.
  • Estos hallazgos sugieren que la hipercontractilidad de LV o el aumento de la tensión de la pared sistólica no desencadenan síncope neuralmente mediada a través de la activación de los mecanorreceptores de LV.