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El uso de protector solar de amplio espectro y el desarrollo de nuevos nevi en niños blancos: un ensayo controlado
R P Gallagher1, J K Rivers, T K Lee
1Cancer Control Research Program, British Columbia Cancer Agency, 600 W Tenth Ave, Vancouver, British Columbia, Canada V5Z 4E6. rickg@bccancer.bc.ca
JAMA
|June 24, 2000
Resumen
El uso de protector solar de amplio espectro redujo significativamente el desarrollo de nuevos lunares en niños blancos. Este efecto fue particularmente pronunciado en niños con pecas, lo que sugiere un papel clave para la protección solar en la prevención de los factores de riesgo de melanoma.
Área de la Ciencia:
- Dermatología Pediátrica.
- La medicina preventiva es la medicina preventiva de las enfermedades.
- Oncología Oncología.
Sus antecedentes:
- La alta densidad de nevos melanocíticos es un factor de riesgo conocido para el melanoma maligno cutáneo.
- El desarrollo de los nervios, especialmente en los niños, está fuertemente asociado con la exposición solar.
- Las estrategias de intervención temprana son cruciales para mitigar el riesgo de melanoma.
Objetivo del estudio:
- Investigar la eficacia del protector solar de amplio espectro y alto factor de protección solar (SPF) en la prevención del desarrollo de nervios.
- Para determinar si el uso de protector solar puede atenuar la formación de nuevos nevi en niños blancos.
- Evaluar el impacto del protector solar en un factor de riesgo clave para el melanoma.
Principales métodos:
- Un ensayo controlado aleatorizado en el que participaron 309 escolares blancos (grados 1 y 4) en Vancouver, Columbia Británica.
- El grupo de intervención (n=222) recibió protector solar de amplio espectro SPF 30, mientras que el grupo de control (n=236) no recibió protector solar ni asesoramiento.
- Los recuentos de nevi se enumeraron al inicio y después de 3 años, con la adquisición de nuevos nevi comparados entre grupos.
Principales resultados:
- Los niños que usaban protector solar desarrollaron significativamente menos nuevos nevi en comparación con el grupo de control (contabilidad media 24 vs 28, P=.048).
- Se observó una interacción significativa entre las pecas y el grupo de estudio, destacando un mayor beneficio para los niños con pecas.
- El modelado sugirió que los niños con pecas que usan protector solar podrían experimentar una reducción del 30% al 40% en el desarrollo de nuevos nervios.
Conclusiones:
- Los protectores solares de amplio espectro demuestran potencial para atenuar el desarrollo de nervios en niños blancos.
- El efecto protector del protector solar es particularmente significativo para los niños con pecas.
- El uso constante de protector solar puede ser una estrategia efectiva para reducir los factores de riesgo de melanoma en la infancia.
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