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La velocidad de flujo de la arteria coronaria está relacionada con el área de la luz y la masa ventricular izquierda
H V Anderson1, M J Stokes, M Leon
1University of Texas Health Science Center and Hermann Hospital, Houston 77225, USA. skipand@heart.med.uth.tmc.edu
Circulation
|July 6, 2000
Resumen
La velocidad de flujo coronario en reposo está relacionada con el tamaño del corazón.
Área de la Ciencia:
- Fisiología cardiovascular fisiología cardiovascular.
- Enfermedad de las arterias coronarias Enfermedad de las arterias coronarias
- La hemodinámica es la hemodinámica.
Sus antecedentes:
- La velocidad del flujo coronario exhibe una significativa variabilidad interindividual en reposo.
- La reserva de flujo coronario (relación entre la velocidad hiperémica y la velocidad de reposo) es un índice comúnmente estudiado.
- El principio de continuidad del flujo fue investigado para modelar el flujo coronario en reposo.
Objetivo del estudio:
- Para probar la hipótesis de que el principio de continuidad del flujo puede modelar el flujo coronario en reposo.
- Para examinar la relación entre el tamaño de la luz coronaria y la velocidad de reposo.
- Para investigar el impacto de la aterosclerosis coronaria en la dinámica del flujo en reposo.
Principales métodos:
- Un cable Doppler utilizado para medir las velocidades de reposo e hiperemia en 59 pacientes.
- Cálculo cuantitativo del área de la sección transversal de la luz y las longitudes de las ramas coronarias distales.
- Estimación de la masa regional del ventrículo izquierdo y el área del lumen en relación a la masa (A/m).
Principales resultados:
- La velocidad de reposo (V) mostró una relación inversa con la relación A/m (V=46.5/(A/m)).
- La relación A / m disminuyó con el aumento de la gravedad de la enfermedad de la arteria descendente anterior izquierda.
- La velocidad pico promedio en reposo tendía a aumentar con la aterosclerosis coronaria más grave.
Conclusiones:
- La velocidad de flujo de la arteria coronaria en reposo está inversamente relacionada con el área del lumen a la relación de masa ventricular izquierda regional.
- Las velocidades de reposo elevadas indican un tamaño insuficiente de la luz para el lecho miocárdico, típico de la aterosclerosis coronaria difusa.
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