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Updated: Jul 13, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
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La conformación productiva del ácido araquidónico unido a la prostaglandina sintasa

M G Malkowski1, S L Ginell, W L Smith

  • 1Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824-1319, USA.

Science (New York, N.Y.)
|September 16, 2000
PubMed
Resumen

Se determinó la estructura de la prostaglandina H sintasa-1 (PGHS-1) con ácido araquidónico (AA) unido. La estructura revela cómo AA se une en una conformación lista para la síntesis de prostaglandinas, un paso clave dirigido por los AINE.

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