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La diabetes mellitus sensible a los corticosteroides está asociada con pancreatitis autoinmune
Lancet (London, England)
|October 19, 2000
Resumen
La pancreatitis autoinmune puede conducir a la diabetes. El tratamiento con corticosteroides, como la prednisolona, mejora la secreción de insulina y el control del azúcar en la sangre en pacientes con esta afección.
Área de la Ciencia:
- Endocrinología Endocrinología.
- Gastroenterología y Gastroenterología.
- Inmunología Inmunología.
Sus antecedentes:
- La pancreatitis autoinmune (PAI) es una condición inflamatoria crónica con posibles vínculos con la disfunción endocrina.
- La relación entre la AIP y la diabetes mellitus, particularmente con respecto a los resultados del tratamiento, requiere una mayor aclaración.
Objetivo del estudio:
- Para investigar la relación entre la pancreatitis autoinmune y la diabetes.
- Para evaluar el efecto del tratamiento con corticosteroides en el control glucémico en pacientes con pancreatitis autoinmune.
Principales métodos:
- Un estudio de cohorte de 2220 pacientes con sospecha de pancreatitis crónica.
- Análisis de cuatro pacientes diagnosticados con pancreatitis crónica autoinmune.
Principales resultados:
- Los cuatro pacientes con pancreatitis crónica autoinmune también tenían diabetes.
- El tratamiento con prednisolona mejoró la secreción de insulina.
- El tratamiento con prednisolona mejoraba el control glucémico.
Conclusiones:
- La pancreatitis autoinmune está fuertemente asociada con la diabetes.
- La terapia con corticosteroides es un tratamiento eficaz para la diabetes en pacientes con pancreatitis autoinmune.
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