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Updated: Jul 9, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

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Published on: March 22, 2012

Bases estructurales para la transducción de señales por los dominios del receptor Toll/interleucina-1

Y Xu1, X Tao, B Shen

  • 1Department of Biological Sciences, Columbia University, New York, New York 10027, USA.

Nature
|November 18, 2000
PubMed
Resumen

Los receptores tipo peaje (TLR) son clave para la inmunidad. Una mutación específica en su dominio TIR interrumpe la señalización inmune al evitar la interacción con la molécula del adaptador MyD88, lo que afecta la defensa del huésped.

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