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Updated: Jun 30, 2026

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Mecanismos en el fracaso de infliximab para la enfermedad de Crohn

S Nikolaus1, A Raedler, T Kühbacker

  • 1Christian-Albrechts-University, First Department of Medicine, Kiel, Germany.

Lancet (London, England)
|November 18, 2000
PubMed
Resumen

Inicialmente, el infliximab mejoró los síntomas de la enfermedad de Crohn en la mayoría de los pacientes, pero muchos reaparecieron cuando los marcadores inmunes como el factor de necrosis tumoral alfa (TNF-alfa) y el factor nuclear kappa B (NFkappaB) se reactivaron antes de que regresaran los síntomas.

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