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Measuring and Altering Mating Drive in Male Drosophila melanogaster
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El control genético y la evolución de los caracteres sexualmente dimórficos en Drosophila
1Howard Hughes Medical Institute and Laboratory of Molecular Biology, University of Wisconsin-Madison, 53706-1596, USA.
Nature
|December 16, 2000
Resumen
El gen bric à brac (bab) controla los rasgos abdominales de la mosca de la fruta, como la pigmentación y la forma del segmento. Los cambios regulatorios en la evolución del gen bab son clave para el desarrollo del dimorfismo sexual en Drosophila.
Área de la Ciencia:
- Genética evolutiva de la genética evolutiva.
- Biología del desarrollo Biología del desarrollo.
- Comportamiento animal Comportamiento animal.
Sus antecedentes:
- El grupo de especies melanogaster de Drosophila exhibe una evolución reciente de pigmentación abdominal sexualmente dimórfica y morfología de segmentos.
- Los fundamentos genéticos de estos rasgos sexualmente dimórficos siguen siendo en gran parte inexplorados.
Objetivo del estudio:
- Para identificar el gen que controla los rasgos abdominales sexualmente dimórficos en Drosophila.
- Investigar los mecanismos reguladores y el significado evolutivo de este gen en el dimorfismo sexual.
Principales métodos:
- Análisis de los patrones de expresión génica en especies de Drosophila sexualmente dimórficas y monomórficas.
- Investigar los insumos regulatorios de las vías homeóticas y de determinación del sexo en el gen identificado.
- Evaluación del impacto de la pigmentación específica del gen en las preferencias de apareamiento.
Principales resultados:
- El gen bric à brac (bab) fue identificado como el regulador clave de la pigmentación abdominal y la morfología del segmento.
- La expresión génica de bab está modulada específicamente por segmento y sexo en las especies dimórficas, en contraste con la expresión uniforme en las especies monomórficas.
- Los patrones de pigmentación especificados por bab influyen en las preferencias de apareamiento de Drosophila.
Conclusiones:
- Los cambios regulatorios en el locus bab han sido fundamentales en la evolución del dimorfismo sexual en Drosophila.
- El gen bab integra vías homeóticas y de determinación del sexo para especificar rasgos sexualmente dimórficos.
- La selección sexual probablemente contribuyó a la evolución de la regulación del gen bab debido a su papel en los comportamientos de apareamiento.
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