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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
El consumo de alcohol y el riesgo de claudicación intermitente en el Framingham Heart Study
L Djoussé1, D Levy, J M Murabito
1Department of Medicine, Section of Preventive Medicine & Epidemiology Boston University School of Medicine, Boston, Massachusetts, USA. ldjousse@bu.edu
Circulation
|January 11, 2000
Resumen
El consumo moderado de alcohol, especialmente vino y cerveza, puede reducir el riesgo de desarrollar claudicación intermitente (CI). El riesgo más bajo se observó en hombres que consumían 13-24 g/día y mujeres que consumían 7-12 g/día.
Área de la Ciencia:
- Epidemiología cardiovascular.
- Investigación sobre el alcohol.
- Enfermedad de las arterias periféricas.
Sus antecedentes:
- La claudicación intermitente (CI) está relacionada con un mayor riesgo de enfermedad cardiovascular (ECV).
- La asociación entre la ingesta de alcohol y el desarrollo de CI no está bien establecida.
- Estudios anteriores muestran resultados contradictorios con respecto al consumo de alcohol y el riesgo de CI.
Objetivo del estudio:
- Investigar la relación entre el consumo de alcohol y la incidencia de claudicación intermitente.
- Examinar cómo los diferentes tipos de bebidas alcohólicas influyen en el riesgo de CI.
- Para analizar los datos de los participantes en el Estudio del Corazón Framingham.
Principales métodos:
- Categorizó el consumo de alcohol en cinco niveles (0, 1-6, 7-12, 13-24, >/=25 g/d).
- Se siguió a 414 sujetos durante una media de 6,8 años para el desarrollo de la CI.
- Utilizó la regresión multivariada de Cox para analizar la asociación entre la ingesta de alcohol y el riesgo de IC.
Principales resultados:
- Se observó una curva en forma de J para la incidencia de CI en todas las categorías de consumo de alcohol para hombres y mujeres.
- El riesgo más bajo de IC se encontró en 13-24 g / d para los hombres (HR: 0.67) y 7-12 g / d para las mujeres (HR: 0.44).
- Un efecto protector contra la IC se asoció principalmente con el consumo moderado de vino y cerveza.
Conclusiones:
- El consumo moderado de alcohol parece tener un efecto protector contra la claudicación intermitente.
- Se identificaron niveles de protección óptimos de 13-24 g/día para los hombres y de 7-12 g/día para las mujeres.
- El consumo de vino y cerveza mostró la asociación más significativa con la reducción del riesgo de CI.
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