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La estructura cristalina de un complejo beta-catenina/Tcf tiene una estructura

T A Graham1, C Weaver, F Mao

  • 1Department of Biological Structure University of Washington 98195, Seattle, WA, USA.

Cell
|January 4, 2001
PubMed
Resumen

Los investigadores determinaron la estructura cristalina de la beta-catenina unida al Tcf3-CBD, revelando sitios críticos de unión. Este hallazgo ofrece potencial para el diseño de fármacos moleculares dirigidos a la vía de señalización Wnt.

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