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La dispersión Qt no tiene información de pronóstico para pacientes con insuficiencia cardíaca congestiva avanzada y
1Copenhagen University Hospital, Gentofte, Denmark.
Circulation
|February 15, 2001
Resumen
La dispersión QT no predice la mortalidad en pacientes con insuficiencia cardíaca congestiva avanzada (ICF). Este estudio no encontró ningún vínculo entre la dispersión del intervalo QT y la muerte por cualquier causa, cardíaca o arritmica en pacientes con insuficiencia cardíaca congestiva.
Área de la Ciencia:
- Cardiología Cardiología.
- Electrofisiología y electrofisiología.
- Investigación de la insuficiencia cardíaca Investigación de la insuficiencia cardíaca.
Sus antecedentes:
- La dispersión QT es un potencial marcador de pronóstico para eventos taquiárritmicos y mortalidad.
- Su valor pronóstico en pacientes con insuficiencia cardíaca congestiva (ICH) sigue sin estar claro.
Objetivo del estudio:
- Investigar el valor pronóstico de la dispersión QT en pacientes con insuficiencia cardíaca congestiva avanzada y disfunción ventricular izquierda.
Principales métodos:
- Análisis de ECG basal de 703 pacientes con insuficiencia cardiaca congestiva avanzada en el estudio Diamond-CHF.
- La mediana de seguimiento fue de 18 meses, evaluando la mortalidad por todas las causas, cardíaca y aritmética cardíaca.
- Análisis de supervivencia para determinar la información pronóstica derivada de la dispersión QT.
Principales resultados:
- La dispersión QT media fue de 70 ms, sin diferencias significativas entre sobrevivientes y no sobrevivientes.
- La dispersión QT no mostró valor pronóstico para la mortalidad por cualquier causa (P=0,74).
- La dispersión QT no predijo la mortalidad cardíaca (P=0,55) o la mortalidad por arritmia cardíaca (P=0,38).
Conclusiones:
- La dispersión QT carece de valor pronóstico para los resultados de mortalidad en pacientes con insuficiencia cardiaca congestiva avanzada y función sistólica ventricular izquierda reducida.
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