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Updated: Jun 24, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 18, 2010

Determinantes estructurales para la regulación de la fosfodiesterasa por una proteína G a 2.0 A

K C Slep1, M A Kercher, W He

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06511, USA. kcs@mail.csb.yale.edu

Nature
|March 10, 2001
PubMed
Resumen

Las perspectivas estructurales sobre la terminación de la señal visual revelan cómo la unión de la subunidad alfa (αt) de transducina a la subunidad gamma de la fosfodiesterasa GMP cíclica (PDEγ) mejora la recuperación visual. Esta interacción potencia el reclutamiento de RGS9 para la terminación de la señal.

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