Video Experimental Relacionado

Updated: Jul 15, 2026

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes
10:05

In Vitro Analysis of PDZ-dependent CFTR Macromolecular Signaling Complexes

Published on: August 13, 2012

Transporte aberrante de HCO3 dependiente del CFTR en mutaciones asociadas con la fibrosis quística

J Y Choi1, D Muallem, K Kiselyov

  • 1Department of Physiology, The University of Texas Southwestern Medical Center, Dallas 75390, USA.

Nature
|March 10, 2001
PubMed
Resumen

La fibrosis quística (FC) surge de mutaciones en el regulador de conductividad transmembrana de la fibrosis quística (CFTR). La alteración del transporte de bicarbonato (HCO3-) de la CFTR, no solo la función del canal de cloruro (Cl-), es crucial para la patogénesis de la FQ.

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