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Updated: Jun 14, 2026

Optical Mapping of Intra-Sarcoplasmic Reticulum Ca2+ and Transmembrane Potential in the Langendorff-perfused Rabbit Heart
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La disminución del contenido de calcio en el retículo sarcoplásmico es responsable del acoplamiento defectuoso de

I A Hobai1, B O'Rourke

  • 1Institute of Molecular Cardiobiology, Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Md, USA.

Circulation
|March 21, 2001
PubMed
Resumen

El contenido reducido de calcio en el retículo sarcoplásmico (Ca(SR), sin alterar el acoplamiento excitación-contracción, explica la disminución de los transitorios de calcio intracelular en la insuficiencia cardíaca. Las terapias dirigidas a Ca(SR) pueden restaurar el manejo normal del calcio.

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