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IFNgamma y los linfocitos previenen el desarrollo de tumores primarios y dan forma a la inmunogenicidad tumoral

V Shankaran1, H Ikeda, A T Bruce

  • 1Department of Pathology and Immunology, Center for Immunology, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, Missouri 63110, USA.

Nature
|April 27, 2001
PubMed
Resumen

El sistema inmunológico, incluidos los linfocitos y el interferón gamma (IFNγ), actúa como un supresor tumoral al prevenir el desarrollo del cáncer. Sin embargo, este proceso también selecciona las células cancerosas que pueden evadir la detección inmune.

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