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Updated: Jun 29, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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Papel de la Rab9 GTPasa en la facilitación del reclutamiento de receptores por TIP4747

K S Carroll1, J Hanna, I Simon

  • 1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305-5307, USA.

Science (New York, N.Y.)
|May 19, 2001
PubMed
Resumen

TIP47 se une a la Rab9 GTPasa activa, aumentando su afinidad por los receptores de manosa 6-fosfato (MPR). Esta interacción es crucial para el transporte eficiente de MPRs de endosoma a Golgi, vinculando la selección de carga a la actividad de la Rab GTPasa.

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