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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Insuficiencia cardíaca congestiva asociada con el itraconazol
Lancet (London, England)
|June 14, 2001
Resumen
El itraconazol, un antifúngico, puede causar insuficiencia cardíaca congestiva. Este riesgo es resaltado por 58 casos reportados, lo que lleva a advertencias médicas actualizadas para este importante medicamento antifúngico.
Área de la Ciencia:
- Farmacología Farmacología.
- Cardiología Cardiología.
- Enfermedades infecciosas Enfermedades infecciosas.
Sus antecedentes:
- El itraconazol es un medicamento antimicótico sintético utilizado para la onicomicosis y las infecciones fúngicas sistémicas.
- Los estudios farmacológicos indican que el itraconazol puede ejercer efectos negativos inotrópicos.
- Los datos del Sistema de Reporte de Eventos Adversos (FAERS) de la Administración de Alimentos y Medicamentos de los Estados Unidos han señalado asociaciones potenciales entre el uso de itraconazol y la insuficiencia cardíaca congestiva.
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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
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