Video Experimental Relacionado
Updated: May 7, 2026
07:51
Implantation of a Carotid Cuff for Triggering Shear-stress Induced Atherosclerosis in Mice
Published on: January 13, 2012
Las placas carotídicas ecolucentes ultrasónicas predicen futuros accidentes cerebrovasculares
M L Grønholdt1, B G Nordestgaard, T V Schroeder
1Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Osaka, Japan. mlg@dadlnet.dk
Circulation
|July 4, 2001
Resumen
Las placas carotídicas ecolucentes predicen el riesgo de accidente cerebrovascular en pacientes sintomáticos, pero no en los asintomáticos. La ecolucencia de la placa y el grado de estenosis pueden mejorar la evaluación del riesgo de accidente cerebrovascular y la selección del paciente para la endarterectomía carotídea.
Área de la Ciencia:
- Neurología Neurología.
- La medicina vascular es una medicina vascular.
- Imágenes médicas de imágenes médicas.
Sus antecedentes:
- La estenosis de la arteria carótida es un factor de riesgo significativo para el accidente cerebrovascular isquémico.
- Predecir el riesgo de accidente cerebrovascular en pacientes con aterosclerosis carotídea sigue siendo un desafío clínico.
- Las características de la placa, como la eco-lucencia, pueden ofrecer un valor pronóstico.
Objetivo del estudio:
- Para evaluar prospectivamente si la ecolucencia de la placa carotídea predice el desarrollo del accidente cerebrovascular.
- Para evaluar esta predicción en pacientes previamente sintomáticos y asintomáticos.
- Para determinar si la ecolucencia mejora la estratificación del riesgo de accidente cerebrovascular más allá del grado de estenosis.
Principales métodos:
- Estudio prospectivo de 246 pacientes (111 asintomáticos, 135 sintomáticos) con >=50% estenosis de la arteria carótida.
- La ecografía de modo B de alta resolución con procesamiento de imágenes asistido por computadora evaluó la ecogenicidad de la placa.
- La ecografía Doppler evaluó el grado de estenosis de la arteria carótida.
- Seguimiento de los accidentes cerebrovasculares isquémicos ipsilaterales durante 4.4 años.
Principales resultados:
- Se observaron 44 accidentes cerebrovasculares isquémicos ipsilaterales durante el seguimiento.
- En pacientes sintomáticos, las placas ecolucentes aumentaron significativamente el riesgo de accidente cerebrovascular (riesgo relativo = 3,1).
- Una mayor estenosis (80-99%) mostró una tendencia hacia un mayor riesgo (RR=1.4) en pacientes sintomáticos, pero la ecolocidad fue un predictor más fuerte.
- No se encontró una asociación significativa entre la ecolucencia de la placa y el riesgo de accidente cerebrovascular en pacientes asintomáticos.
Conclusiones:
- Las placas carotídicas ecolucentes están asociadas con el riesgo futuro de accidente cerebrovascular en individuos sintomáticos con estenosis significativa.
- La ecolucencia de la placa, además de la gravedad de la estenosis, puede mejorar la selección del paciente para la endarterectomía carotídea.
- Este marcador de imagen no parece predecir el riesgo de accidente cerebrovascular en pacientes asintomáticos con estenosis carotídea.
Videos de Conceptos Relacionados
01:20Imaging Studies for Cardiovascular System II:Types of Echocardiography
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
01:30Atherosclerosis I: Introduction
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...