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Estructura cristalina de la glucógeno sintasa quinasa 3 beta: base estructural para la especificidad del sustrato

R Dajani1, E Fraser, S M Roe

  • 1Section of Structural Biology, Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, United Kingdom.

Cell
|July 7, 2001
PubMed
Resumen

La glucógeno sintasa quinasa 3 beta (GSK3 beta) está activa por defecto, fosforilando objetivos. Su estructura revela cómo se une a los sustratos y se inhibe, ofreciendo información sobre las vías de señalización.

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