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La exposición a la fórmula a base de soja en la infancia y los resultados endocrinológicos y reproductivos en la edad
B L Strom1, R Schinnar, E E Ziegler
1University of Pennsylvania, Center for Clinical Epidemiology and Biostatistics, 824 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104-6021, USA. bstrom@cceb.med.upenn.edu
JAMA
|August 22, 2001
Resumen
La exposición infantil a la fórmula de soja no mostró diferencias significativas en la salud a largo plazo en comparación con la fórmula de leche de vaca. Algunas mujeres informaron sangrado menstrual más prolongado y molestias, lo que justifica una mayor investigación sobre los efectos de las isoflavonas de soja.
Área de la Ciencia:
- Endocrinología Endocrinología.
- Nutrición pediátrica para niños.
- Salud reproductiva y salud reproductiva.
Sus antecedentes:
- Los fitoestrógenos, como las isoflavonas de soja, influyen en los estados dependientes de las hormonas.
- Los bebés alimentados con fórmula de soja reciben altas dosis de fitoestrógenos durante los períodos críticos de desarrollo.
- Existen datos limitados sobre los impactos a largo plazo en la salud de la exposición a fórmulas de soja para lactantes.
Objetivo del estudio:
- Investigar la asociación entre el consumo de leche de soja para lactantes y los resultados de salud en la edad adulta joven.
- Para examinar específicamente los efectos a largo plazo en la salud reproductiva en adultos expuestos a la fórmula de soja como bebés.
Principales métodos:
- Un estudio de cohorte retrospectivo en el que participaron adultos de entre 20 y 34 años.
- Los participantes fueron categorizados en función de la alimentación infantil: fórmula de soja (n = 248) o fórmula de leche de vaca (n = 563).
- Los datos recopilados incluyeron la maduración puberal autoinformada, el historial reproductivo y el estado de salud general.
Principales resultados:
- No se encontraron diferencias estadísticamente significativas en más de 30 resultados de salud o reproductivos entre los grupos de fórmulas de soja y leche de vaca.
- Las mujeres expuestas a la fórmula de soja informaron una duración ligeramente más larga del sangrado menstrual (0,37 días).
- Las mujeres expuestas a la fórmula de soja informaron un aumento de la incomodidad menstrual (RR 1.77).
Conclusiones:
- La exposición infantil a la fórmula de soja no parece dar lugar a resultados adversos para la salud general o reproductiva en comparación con la fórmula de leche de vaca.
- Si bien algunos hallazgos sobre las características menstruales requieren más investigación, el estudio proporciona tranquilidad con respecto a la seguridad de la fórmula infantil de soja.
- Los efectos a largo plazo de las isoflavonas de soja de la fórmula infantil requieren una exploración continua.
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