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Coordinación de un interruptor de transcripción por HMGI(Y) acetilación

N Munshi1, T Agalioti, S Lomvardas

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, 630 West 168th Street, New York, NY 10032, USA.

Science (New York, N.Y.)
|August 11, 2001
PubMed
Resumen

El control dinámico de la expresión génica del interferón-beta (IFN-beta) se basa en el complejo del enhanceosoma. Su montaje y desmontaje están regulados por la acetilación HMGI ((Y), con sitios distintos que influyen en la estabilidad y la transcripción.

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