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Un papel esencial para el BAFF en el desarrollo normal de las células B a través de una vía independiente de BCMA

B Schiemann1, J L Gommerman, K Vora

  • 1Biogen, 14 Cambridge Center, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|August 18, 2001
PubMed
Resumen

El factor de activación de las células B (BAFF) es esencial para el desarrollo de las células B. Los ratones con deficiencia de BAFF mostraron una pérdida significativa de linfocitos B, destacando el papel crítico de BAFF en la maduración de las células inmunes.

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