Video Experimental Relacionado
Updated: Aug 5, 2026

10:10
Drosophila Larval NMJ Immunohistochemistry
Published on: March 28, 2009
El estado fundamental del apéndice ventral en Drosophila
1Department of Biochemistry and Molecular Biophysics, Columbia University, 701 West 168 Street, New York, NY 10032, USA.
Resumen
En las moscas de la fruta, los apéndices se desarrollan a partir de un precursor común. Sin instrucciones genéticas específicas, estos apéndices forman una pierna simple, de dos segmentos, lo que sugiere una vía evolutiva para el desarrollo de la pierna.
Área de la Ciencia:
- Biología del desarrollo Biología del desarrollo.
- Biología evolutiva Biología evolutiva.
- Genética La genética.
Sus antecedentes:
- Las moscas de la fruta (Drosophila melanogaster) poseen apéndices ventrales serialmente homólogos como antenas y patas.
- Estos apéndices se distinguen por genes selectores únicos, lo que implica un estado básico de desarrollo común.
- Comprender este estado fundamental es clave para explicar la diversidad de los apéndices.
Objetivo del estudio:
- Para investigar la morfología de los apéndices ventrales en Drosophila melanogaster cuando la actividad del gen selector está ausente.
- Determinar la naturaleza del estado de base común del cual surgen diversos apéndices.
Principales métodos:
- Manipulación genética en Drosophila melanogaster para eliminar la actividad del gen selector.
- Análisis de la morfología del apéndice ventral resultante, centrándose en la segmentación a lo largo del eje proximo-distal.
Principales resultados:
- Los apéndices ventrales formados sin la actividad del gen selector exhiben una estructura parecida a una pierna.
- Estos apéndices parecidos a piernas están simplificados, consistiendo en sólo dos segmentos: un segmento proximal y un tarso distal.
Conclusiones:
- El apéndice parecido a una pierna formado en ausencia de genes selectores representa el estado básico fundamental.
- Este hallazgo sugiere que los apéndices parecidos a patas podrían haber evolucionado a partir de un precursor que no requería la actividad del gen selector.
Videos de Conceptos Relacionados
The Thoracic Cage: Sternum
The thoracic or rib cage forms the body's thorax (chest) portion. Its primary function in the body is to protect vital organs in the thoracic cavity, such as the heart and the lungs. It consists of 12 pairs of ribs with their costal cartilages and the sternum. The ribs are anchored posteriorly to the 12 thoracic vertebrae (T1-T12).
The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid process.
The sternum is the elongated bony structure on the anterior side of the thoracic cage. It consists of three parts: the manubrium, the body, and the xiphoid process.
Peritoneum
The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Gross Anatomy of the Stomach
The human stomach is a vital part of the digestive system, performing multiple functions. It is located within the peritoneum, a serous membrane that lines the abdominal cavity. The stomach plays a central role in processing food substances and interacts with other digestive organs through coordinated digestive processes. The stomach has a characteristic J-shape and is divided into four main regions. The cardia is the first section where the esophagus connects to the stomach and is the entry...
Gross Anatomy of the Liver
The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Pancreas
The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short and...
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short and...
Ovaries
The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of cuboidal...
On the ovarian surface, a layer of cuboidal...

