Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Direct Motor Pathways01:11

Direct Motor Pathways

The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and the...
Respiration Pathways01:26

Respiration Pathways

Cellular respiration is a fundamental metabolic process that enables organisms to generate energy from organic molecules. One of its central pathways is the tricarboxylic acid (TCA) cycle, also known as the Krebs cycle, which plays a crucial role in energy production and biosynthetic processes.Conversion of Pyruvate to Acetyl-CoAThe pyruvate generated from glycolysis undergoes oxidative decarboxylation by the pyruvate dehydrogenase complex, producing acetyl-CoA, one molecule of NADH, and one...
Transmission of Pathogens01:24

Transmission of Pathogens

Pathogens spread from their reservoirs to susceptible hosts through three main routes: contact transmission, vehicle transmission, and vector transmission. Each route involves distinct mechanisms of transfer.Contact TransmissionThis category includes direct contact, indirect contact, and droplet transmission:Direct contact involves immediate physical interaction between individuals—such as a handshake—which can spread pathogens like Streptococcus pyogenes, the bacterium responsible for...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

Negative information for motif discovery.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2004
Same author

Serial regulation of transcriptional regulators in the yeast cell cycle.

Cell·2001
Same author

Fast optimal leaf ordering for hierarchical clustering.

Bioinformatics (Oxford, England)·2001
Same author

Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2001
Same author

Design and implementation of computational systems based on programmed mutagenesis.

Bio Systems·2000
Same author

Automated constraint-based nucleotide sequence selection for DNA computation.

Bio Systems·2000
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Jun 30, 2026

Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames
10:29

Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames

Published on: June 1, 2016

Caminos ardientes a través de las montañas genéticas.

D K Gifford1

  • 1Department of Computer Science, Massachusetts Institute of Technology, 200 Technology Square, Cambridge, MA 02139, USA. gifford@mit.edu

Science (New York, N.Y.)
|September 15, 2001
PubMed
Resumen
Este resumen es generado por máquina.

El análisis de datos de alto rendimiento ofrece información sobre las funciones celulares. La destilación de estos datos en modelos computacionales predictivos es clave para comprender las enfermedades y desarrollar nuevas terapias.

Más Videos Relacionados

Producing, Characterizing and Quantifying Biochar in the Woods Using Portable Flame Cap Kilns
07:27

Producing, Characterizing and Quantifying Biochar in the Woods Using Portable Flame Cap Kilns

Published on: January 5, 2024

Continuous In-woods Production of Biochar Using a Trailer-Mounted Air Curtain Burner
03:42

Continuous In-woods Production of Biochar Using a Trailer-Mounted Air Curtain Burner

Published on: April 5, 2024

Videos de Experimentos Relacionados

Last Updated: Jun 30, 2026

Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames
10:29

Experimental Methodology for Estimation of Local Heat Fluxes and Burning Rates in Steady Laminar Boundary Layer Diffusion Flames

Published on: June 1, 2016

Producing, Characterizing and Quantifying Biochar in the Woods Using Portable Flame Cap Kilns
07:27

Producing, Characterizing and Quantifying Biochar in the Woods Using Portable Flame Cap Kilns

Published on: January 5, 2024

Continuous In-woods Production of Biochar Using a Trailer-Mounted Air Curtain Burner
03:42

Continuous In-woods Production of Biochar Using a Trailer-Mounted Air Curtain Burner

Published on: April 5, 2024

Área de la Ciencia:

  • Genómica y Biología de Sistemas.
  • Biología computacional Biología computacional.
  • Ciencia de datos biomédicos Ciencia de datos biomédicos.

Sus antecedentes:

  • La generación de datos de alto rendimiento está revolucionando la investigación biológica.
  • La interpretación computacional de datos biológicos complejos es un desafío significativo.
  • Los modelos predictivos son cruciales para comprender los sistemas biológicos y los mecanismos de las enfermedades.

Objetivo del estudio:

  • Explorar métodos para obtener descubrimientos a partir de datos de alto rendimiento.
  • Discutir la integración de hallazgos independientes en una visión holística de la función celular.
  • Para resaltar el potencial de los modelos computacionales en el descubrimiento biológico y el desarrollo terapéutico.

Principales métodos:

  • Revisión de las estrategias de análisis de datos de alto rendimiento.
  • Exploración de técnicas de modelado computacional para datos biológicos.
  • Marco para ensamblar descubrimientos independientes en un modelo integral.

Principales resultados:

  • Los datos de alto rendimiento pueden producir conocimientos biológicos significativos.
  • La destilación computacional de datos es esencial para la creación de modelos predictivos.
  • La integración de diversos descubrimientos mejora la comprensión de los procesos celulares.

Conclusiones:

  • Los datos de alto rendimiento, cuando se modelan computacionalmente, proporcionan un enfoque poderoso para la comprensión biológica.
  • Los modelos predictivos derivados de estos datos son vitales para el avance de la investigación de enfermedades y el descubrimiento de fármacos.
  • Se puede construir una imagen completa de la función celular mediante el ensamblaje de descubrimientos independientes basados en datos.