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Reacciones de complejos de vinilideno yodado generados a partir de 1-iodo-1-alquinas y W(CO) 5(thf)
Tomoya Miura1, Nobuharu Iwasawa
1Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo, 152-8551.
Journal of the American Chemical Society
|January 24, 2002
Resumen
Los investigadores sintetizaron complejos iodados de vinilideno de tungsteno a partir de iodoalquinas y precursores del tungsteno. Estos nuevos complejos permiten una eficiente electrociclado 6pi y ciclizaciones endoselectivas para la síntesis orgánica.
Área de la Ciencia:
- Química organometálica Química orgánica de los metales.
- Química orgánica sintética y orgánica.
Sus antecedentes:
- Los complejos de vinildeno de tungsteno son valiosos intermediarios sintéticos.
- Se necesitan métodos eficientes para generar complejos de vinilideno funcionalizados.
Objetivo del estudio:
- Para sintetizar nuevos complejos de vinildeno de tungsteno yodado.
- Explorar la utilidad de estos complejos en la síntesis orgánica.
Principales métodos:
- Reacción de las 1-iodo-1-alquinas con el W(CO) 5(thf).
- Aplicación de complejos generados en reacciones de ciclización.
Principales resultados:
- Generación exitosa de complejos iodados de vinildeno de tungsteno.
- Se ha demostrado su utilidad en la electrociclado 6pi de estirenos o-iodoetinile.
- Utilidad demostrada en la ciclización endo-selectiva de éteres de enol silílico omega-iodoacetilénico.
Conclusiones:
- El método desarrollado proporciona acceso a complejos versátiles de vinildeno de tungsteno yodado.
- Estos complejos sirven como precursores efectivos para reacciones de ciclización sintéticamente útiles.
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